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Volume 8 Number 12

Guy R. Schenker, D.C.
December, 1997

Dear Doctor,

                        SUGAR BABIES!

     That's what all too many of my patients are -- and I 
don't hesitate to tell them so.  And where does the sugar baby 
lifestyle lead?  To:

- fatigue
- over weight or under weight
- hypoglycemia or diabetes
- anxiety, depression and mood swings
- premature aging

Which is to say that being a sugar baby usually leads to a 
glucogenic or ketogenic metabolic imbalance.

     You learned in last month's Letter about the inadequate 
energy production of your glucogenic and ketogenic patients 
and how this energy insufficiency leads to physical 
devastation, mental depletion, and emotional failure.  We also 
took you in last month's Letter on a step-by-step walk through 
the glucogenic/ketogenic page of your Quick Reference Guide.  
You learned that your glucogenic/ketogenic analysis relates to 
three biochemical abnormalities typical of these patients:

- deficient oxidation activity
- abnormal carbon dioxide levels
- abnormal serum pH

     Your QRG protocol gives you the means to evaluate each of 
your patients for this important metabolic balance in a matter 
of seconds.

     Now look once again at the glucogenic/ketogenic page of 
your QRG for an understanding of how and why you recommend 
supplementation for your glucogenic and ketogenic patients.  
Let us look at the glucogenic side of the page first.
                            - 2 -

     At the top of your glucogenic supplement list is, of 
course, Oxygenic G.  Look at a bottle of Oxygenic G and ask 
yourself why is each of these ingredients included in   
Oxygenic G?  Then, ask yourself another even more important 
question -- why are certain common vitamins and minerals not
included in Oxy G?                                           

     The answers to these questions are quite simple, really.  
Oxygenic G includes a combination of amino acids, vitamins, 
minerals and trace minerals to achieve a desired effect -- to 
increase your glucogenic patients' oxidative energy production 
by facilitating the ketogenic metabolic pathways in which they 
are deficient;  and, to also elevate the low serum pH typical 
of your glucogenic patients.  At the same time we are very 
careful to include in Oxygenic G nothing to push your 
glucogenic patients deeper into the glucogenic metabolic 
pathway in which they are stuck.

     So, for example, you will see in Oxy G vitamin B3 as 
niacinamide and vitamin B12 because they so effectively 
promote alkaline ketogenic metabolism; but, you will see 
absolutely no vitamin B3 as nicotinic acid, nor will you see 
any vitamin B6 because these B vitamins stimulate the acid 
carbohydrate metabolism that is excessive in your glucogenic 
patients.  You will find in Oxygenic G the antioxidant vitamin 
A as palmitate and the bioflavenoids rutin and quercetin -- 
but you will see none of the acid antioxidants like vitamin C.

     What other goodies do you find in Oxy G?  You will find 
ribonucleic acids which satisfy your glucogenic patients' need 
for nucleic acids.  You will also find L-carnitine which gives 
your glucogenic patients a big boost in their ability to 
metabolize the fatty acids which they so desperately need.  
There are four other potently ketogenic amino acids provided 
in your Oxygenic G which help move your glucogenic patients 
into the beta hydroxy butyric acid metabolic pathway so as to 
increase their energy production.

     Nowhere but from NUTRI-SPEC can you find a product 
designed with such nutritional specificity.  No way but with 
your NUTRI-SPEC testing system can you determine a patient's 
need for such a specific supplement.

     As powerful as Oxygenic G is, its benefit to your 
glucogenic patients can be enhanced further with judicious use 
of the other supplements listed in your QRG.  Looking further 
down the list you will next see the amino acids tyrosine and 
phenylalanine.  These are the major ketogenic amino acids and 
are already included in your Oxygenic G.  However, you will 
find patients whose symptomatic picture will clear up more
quickly if you give higher dosages of these amino acids.
                            - 3 -

     These amino acids are particularly beneficial for your
patients suffering from allergies, depression, and fatigue. 
There is one important caution in the use of these amino 
acids, however.  You note that your QRG specifies to not give 
these amino acids to a glucogenic patient who has a large 
pupil.  Why is this?  The reasoning is simple.  All your 
glucogenic patients have a hypoglycemic tendency.  In some of 
these patients their sympathetic system will make a valiant 
attempt to compensate for the low blood sugar.  Some of these 
patients will produce tremendous amounts of the catecholamines 
epinephrine and norepinephrine in their struggle to maintain 
normal blood sugar.  In other words, these patients will be 
continuously in a state of sympathetic over-reactivity in 
compensation for their glucogenic blood sugar.  Tyrosine and 
phenylalanine are precursors to catecholamines and therefore 
are contraindicated in these glucogenic patients.  If you make 
the mistake of giving tyrosine or phenylalanine to glucogenic 
patients with a strong sympathetic compensation you will tend 
to exacerbate many of their glucogenic symptoms including 
nervousness, anxiety, and insomnia.

     What else can you do supplementally for your glucogenic 
patients?  Next in your QRG you see the amino acid methionine.  
We have described methionine in detail in recent Letters.  To 
review -- methionine is lipotrophic.  This means it helps the 
liver process and eliminate excess cholesterol and 
triglycerides.  This is particularly important in some of your 
glucogenic patients because in some individuals the glucogenic 
preponderance of carbohydrate metabolism leaves a deficiency 
of fat metabolism.  This inadequate metabolism of fats can 
lead to elevated cholesterol and triglycerides.  Furthermore, 
many glucogenic patients have inadequate liver capacity for 
eliminating excess fats.  This is due largely to congestion of 
the biliary system and liver resulting from excess 
carbohydrate and insufficient fat intake relative to that 
glucogenic patient's need.  So -- give methionine to all your 
glucogenic patients with elevated blood fats.

     Methionine is also beneficial for your glucogenic 
patients with allergies because of its antihistamine effect.

     The final supplement listed in your QRG for glucogenic 
patients is glutamine.  We talked at great length about 
glutamine in the October Letter and suggest that you review 
that important information now.  The highlight of glutamine's 
use for your glucogenic patients is in its ability to enhance 
biliary function.  Your glucogenic patients have a tendency to 
gall bladder disease accompanied by gall stones.  This results 
from their excess consumption of carbohydrate relative to fat.  
Glutamine supplementation will help liquefy the gall stones 
and increase the flow of bile acids through the gall bladder.
                            - 4 -

     Switch your attention now to the ketogenic column of your 
QRG.  Oxygenic K is the shining star at the top of the list.  
Look at the list of Oxygenic K ingredients with the same 
questions in mind that you asked about Oxy G -- why are these 
nutrients here, and why are only these nutrients here?  You 
will find all the amino acids, vitamins, minerals, and trace 
minerals to enhance glucogenic metabolism and absolutely 
nothing that will further depress glucogenic metabolism.  
Every nutrient that is in Oxygenic K will increase the 
oxidation activity of you ketogenic patient and elevate carbon 
dioxide levels and decrease the serum pH.  Again -- you have 
here specificity that can be obtained nowhere but from 

     Looking further down the list of ketogenic supplements 
you see tyrosine, phenylalanine, and methionine.  Since these 
are three amino acids which also appeared on the glucogenic 
list you may be asking the obvious question -- how can the 
same amino acid supplements be beneficial for patients with 
totally opposite body chemistries?

     Here is the answer.  It is true that tyrosine and 
phenylalanine are ketogenic amino acids and are therefore of 
critical importance for your glucogenic patients.  But -- that 
is not the only role that tyrosine and phenylalanine play in 
the body.  One other important metabolic pathway they 
participate in is as precursors to one of the important steps 
in the Krebs citric acid cycle.  (For those of you who like to 
punish yourself with biochemistry -- it is the fumeric acid 
step at which these amino acids enter the citric acid cycle.)  
When I first started testing these amino acids clinically I 
had no way of knowing whether their major metabolic activity 
would be anti-glucogenic or anti-ketogenic.  Here was a case 
where we got lucky.  It appears that these amino acids push 
glucogenic patients in a ketogenic direction and push 
ketogenic patients in a glucogenic direction.  It did not have 
to work out that way -- and I had no reasonable expectation 
that it would.  But it did.  This is particularly delightful 
news for us as NUTRI-SPEC practitioners because these amino 
acids can be so effective in giving a boost to our patients 
symptomatically.  As with your glucogenic patients the 
tyrosine and phenylalanine can be used for ketogenic symptoms 
of allergies, depression, and fatigue.  Again, however, we 
must be careful not to give these amino acids to our ketogenic 
patients if there is any strong sympathetic tendency.

     Methionine is also beneficial for the liver of your
ketogenic patient.  Methionine assists in detoxification.  It 
facilitates liver function and increases the production of

                            - 5 -

lecithin in the liver.  All of these are highly beneficial for
your ketogenic patients who either suffer from allergies or 
have high cholesterol.  Just be careful not to use methionine 
on ketogenic patients if they have low surface tension 
indicating a dysaerobic tendency.

     Finally on your list of anti-ketogenic supplements is the 
amino acid histidine.  This is another supplement that we 
covered in great detail in the October Newsletter which you 
really should review.  Histidine's use in your ketogenic 
patients is important in those patients who suffer from 
allergies or rheumatoid arthritis or anemia or nausea 
(particularly nausea of pregnancy) or GI ulcers or any auto 
immune disease.  Histidine is so perfectly compatible with the 
ketogenic imbalance because it is the major amino acid which 
enters the Krebs cycle in which these patients are deficient.  
For that reason there is already some histidine in your     
Oxy K -- but additional supplementation is beneficial for many 
of these patients.

     Let's take one more look at your glucogenic/ketogenic 
Sugar Babies.  Sugar handling stress is the very core of this 
particular metabolic control system.  Most of the physical/ 
mental/emotional symptoms found in these patients are the 
result of either high or low blood and brain sugar, or, the 
body's response to dietary carbohydrate.

     Look at page 3 of your QRG.  Under abnormal tests you 
find glucose; and next to glucose in the glucogenic column you 
find a huge word, "NEVER."  Just as a midget cannot be tall 
and an orange cannot be blue -- a glucogenic patient, (by 
definition) cannot be diabetic.  This has been a point of 
confusion for many of you because very often you find diabetic 
patients who test as glucogenic.  The reason for this is 
almost invariably because insulin and the other diabetic 
medications push a person's chemistry in the glucogenic 
direction.  Never treat a diabetic as glucogenic!

     This is an appropriate time to give you a quick summary 
of diabetes.  All diabetic patients are ketogenic and/or 
sympathetic.  That is why both your Oxygenic K and your 
Complex S are loaded with both chromium polynicotinate and 
BMOV Vanadium, two trace minerals which have an amazing 
ability to lower elevated blood sugar.  Should you make the 
mistake of treating a diabetic as glucogenic (or 
parasympathetic) you can expect disastrous consequences.

     What has happened in your ketogenic patients that make
them susceptible to diabetes?  Your ketogenic patients are 
insulin resistant.  These are your classic adult onset,
                            - 6 -

non-insulin dependent diabetics.  Many of your ketogenic 
diabetic patients were actually hypoglcyemic (either 
parasympathetic or perhaps glucogenic) early in life.  They 
have gone through a progression from hypoglycemia to a state 
of disinsulinsim to a state of insulin resistance and, if 
allowed to progress, to diabetes.  There is no lack of insulin 
in these diabetic patients.  In actuality, they have a 
life-long history of over-secreting insulin in response to 
excess carbohydrate intake.  In early years this excess 
insulin output pushes the blood sugar lower and they suffer 
hypoglycemia.  As the years pass the response to insulin 
becomes erratic -- thus a state of disinsulinism when blood 
sugar levels can be either very high or very low.  Eventually 
the patient becomes more and more resistant to insulin.  In 
other words, the patient still puts out tremendous amounts of 
insulin in response to dietary carbohydrate, but the body 
tissues are less sensitive to insulin so the insulin is 
ineffective at pulling the sugar out of the blood.  Your 
ketogenic patients have symptoms associated with the high 
blood sugar, but even more symptoms are associated with the 
high levels of insulin.  High insulin is implicated as a 
causative factor in high blood pressure and in many forms of 
premature aging, and in many hormone imbalances.

     Whether you are dealing with the classic hypoglycemic 
crisis typical of your glucogenic patients or the insulin 
resistance of your ketogenic patients -- you will find that 
the only way to achieve glycemic control in these patients is 
with you NUTRI-SPEC testing and supplementation protocol.  No 
one else can come close to the value you, as a NUTRI-SPEC 
practitioner, offer these patients.


                           Guy R. Schenker, D.C.

P.S:  Mighty Mins are here!  Mighty Mins are here!              

                    MIGHTY MINS ARE HERE!

Mighty Mins?  Yes, Mighty Mins!  Our chewable supplement for 
children is finally available.  It is the child's equivalent 
of Oxygenic B -- and every child you know from 6 months 
through puberty must take this supplement (whether you are 
doing NUTRI-SPEC testing on them or not).  Call us today for 
information and to place your order.


Nutri-Spec Letters