From: Guy R. Schenker, D.C. September, 1999 Dear Doctor, In last month's Letter, you read two case studies of women who each had rather extreme physical and (especially) emotional symptoms. What these women had in common was ... A COMPLETE LOSS OF GLYCEMIC CONTROL ... associated with a glucogenic metabolic imbalance. One interesting point about both these women was that they were both extremely health conscious. Each was rigorously following the diet which is promoted as the healthy ideal by the so-called nutrition authorities of our day. Each patient was, in fact, literally destroying herself with a diet consisting of high carbohydrate and "natural" sugar, while avoiding saturated fat and cholesterol. You will see this theater of the absurd performed among your own patients time and time again. Your glucogenic and parasympathetic patients will be punishing themselves with a high carb, low fat diet. These are your patients who are invariably hypoglycemic and who are (genetically) designed to eat a predominantly fat diet, and who have little tolerance for carbohydrate, and virtually no tolerance for sugar. There are literally millions of these neurotic hypoglycemics out there dutifully feeding their physical and emotional stability with the diet recommended by the authorities. The high carb diet, of course, further feeds their craving for carbs. With such a passionate craving for starches, they easily convince themselves that these must be the foods their bodies need. - 2 - As the months and then years go by, they are quite happy with their diet and quite pleased with themselves for so successfully avoiding the evil high fat foods. Meanwhile the depression and anxiety grow ever further out of control; obesity becomes a further source of both physical and emotional trauma; allergies, arthritis, fatigue, and endless other symptoms also enter the clinical picture. All that these pathetic people really need to completely turn themselves around is for you to shine the light of objectivity into their lives. With your NUTRI-SPEC testing system you can identify their true fundamental metabolic needs within minutes. A total reversal of their dietary habits -- switching to the high fat diet they so desperately need -- will immediately lift the dreary cloud of suffering that has darkened their days. The next act of this drama is just as absurd. Starring your ketogenic and sympathetic patients, it features the severe suffering of those wolfing down 16 ounce steaks in total ignorance of their metabolic needs. Again, the only way to put a stop to this tragedy is with your NUTRI-SPEC system leading these patients out of the darkness. Let us now follow up on last month's hypoglycemic theme with two more case studies. We looked at two glucogenic hypoglycemics -- consider now this para- sympathetic hypoglycemic. Case Study #1: Debbie is a red haired, freckly, blue eyed 37 year old woman who might as well have walked into our office wearing a sign, "I am a classic parasympathetic -- please save me." Here are the highlights of her clinical picture: - severe allergies, for which she takes Claritin daily, and for which she receives allergy shots monthly. - severe anxiety which was exacerbated by Zoloft, and for which she now takes Lorazepam as needed. - insomnia associated with the anxiety -- she wakes up in the middle of the night in a panic attack. - chronic fatigue, which is made worse by her difficulty sleeping. - 3 - - constant indigestion which also causes chest pain and thoracic pain. - her gall bladder was removed one year ago. - Prilosec has been prescribed for her indigestion, but has been of no help. How do we sort through such a complex clinical picture? Do we look for a nutritional approach to the anxiety? Do we give her additional supplements to correct the chronic fatigue? Do we prescribe natural remedies for her digestive problems? Can we find the right combination of antioxidants to cure her allergies? No. No. No. No. We use an analytical system of clinical nutrition -- we let our QRG protocol sort through her 46 objective tests to determine just what she needs to increase her adaptative capacity by balancing her metabolism. Debbie's initial testing showed two imbalances -- parasympathetic, along with a potassium excess acidosis. These two imbalances are very often found concurrently. Both the parasympathetic and potassium excess acidosis patterns are associated with weak adrenal function. In particular, here we are looking at deficient epinepherine and DHEA output. Both these imbalances are exacerbated by excess potassium intake. Both imbalances are totally devastated by juices and fruits, which are a concentrated source of potassium plus sugar plus acids. Guess what kind of diet this patient was following? Her mother had died at an early age of cardiovascular disease. So, Debbie was on a low fat, low cholesterol diet, and was eating freely of complex carbs and fruit -- the foods everyone "knows" are good for all of us, and which are particularly essential to avoid cardiovascular disease. What was the cause of this patient's allergies? Parasympathetic imbalance is associated with excess nasal and pharengial and bronchial secretion, as well as with excess histamine activity. What was the source of the patient's anxiety and fatigue? Parasympathetic imbalance is associated with excess insulin and insufficient catecholamine activity, thus resulting in a strong hypoglycemic tendency. Her anxiety, fatigue and nocturnal panic attacks are classic hypoglycemic symptoms. What about her indigestion? Here was a genetically - 4 - predisposed parasympathetic who desperately needed a high fat intake. What had she been feeding her gall bladder? Almost nothing but starches and sugars. As a result her bile flow through her gall bladder was depressed -- the gall bladder became congested, thus packing full of stones. What do we do for Debbie? We put her on the exact supplement regimen indicated by your QRG analysis -- including Oxy B, Complex P, Tyrosine, Phenylalanine, Glutamine, and sodium glycerophosphate. She was given the NUTRI-SPEC Fundamental Diet, the Parasympathetic Diet, the Potassium Excess Acidosis Diet, and the Prostaglandin Diet. What happened? Debbie should have been back within 7 days for her first follow-up, but was delayed until day 10. What did we find? Her objective test patterns had improved considerably. In fact, her parasympathetic imbalance was no longer testing as positive at all. Because she was following the relatively high fat, low carbohydrate dietary recommendations, she was already in ketosis. While weight loss was not mentioned as one of her goals for pursuing NUTRI-SPEC, it was apparent that she had plenty of adipose that she would rather live without. Now after 10 days on her NUTRI-SPEC regimen she was burning up her excess fat stores. Her next test was 14 days later (24 days after her initial test), at which point she was feeling incredibly better and was totally drug free. She had had no allergy medication, no medication for indigestion, and no anxiety medication. She was premenstrual at that time and was definitely feeling the effects. She noted that all her symptoms tended to be worse when she was premenstrual. (This is typical of parasympathetic patients since estrogen potentiates parasympathetic activity.) But, despite being premenstrual, she somehow was enough in control that she didn't feel the need for her drugs. On that date the patient showed absolutely no metabolic imbalances. We substantially decreased all her supplementation. In the ensuing month, Debbie has continued to do well. She does take both allergy medication and anxiety medication from time to time. But most importantly, she notices a direct correlation between her carbohydrate intake and her various symptoms. In other words, she has seen the direct cause and effect relationship between her lifestyle choices and her health. - 5 - Case Study #2: Bonnie is an interesting case in glycemic control. She tested as a glucogenic hypoglycemic, but in treating her we witnessed some startling changes -- some good, and some apparently less than ideal. Bonnie had three major complaints. The first was menopausal hot flashes. She had stopped menstruating about a year and a half ago and the hot flashes had started at that time. Another major compliant was a loss of bladder control, and this was tied in with her hot flashes. She reported that whenever she got a hot flash she must go to the bathroom to urinate immediately. Finally, Bonnie had a problem with acid reflux which was associated with pain under her right ribs, and which had been attributed to a gall bladder problem. One other noteworthy point from Bonnie's history was that she had known that she was hypoglycemic since she was a teenager. As a teen her blood sugar was seen to drop as low as 35 overnight. She was now 52 and no longer considered hypoglycemia a major complaint since she had learned very early in the game that she needed to eat a fair amount of meat to control her sugar. Upon initial testing Bonnie showed three imbalances: dysaerobic, glucogenic and metabolic acidosis. She was given the indicated supplementation which included Oxy B, Oxy D, Oxy D+, Oxy G, Formula EW, Sodium Glycerophosphate, di-sodium phosphate, sodium citrate and glutamine. She was also put on the Dysaerobic, Glucogenic, and Metabolic Acidosis Diets with a strong emphasis on totally avoiding fruit, sugar and all sources of polyunsaturated oils. The foods she needed to emphasize in her diet were meat, fish, poultry, eggs and butter. On her first follow-up test in 7 days, Bonnie showed spectacular improvement. Not one NUTRI-SPEC metabolic imbalance was evident. There was so much improvement that everyone of her supplements (except Oxy B, of course,) was reduced substantially in quantity as per the QRG analysis. Accompanying the amazing improvement in her objective test patterns was Bonnie's report that her hot flashes had decreased to the point where they were nothing but a very mild nuisance. At the same time in the past week she had had more energy than she could remember having in years. We scheduled Bonnie for her next follow-up in 3 weeks. One week later, however, Bonnie phoned our office to say that her hot flashes had come surging back. We - 6 - advised her to increase a few of her supplements back up to the original dosage. When she did report for her next appointment, her tests showed that her dysaerobic and metabolic acidosis patterns were still no longer evident, but her glucogenic test pattern had returned. We adjusted her supplements as per the QRG, and scheduled an appointment in 4 weeks. Now is when things got interesting. Bonnie phoned our office 2 days later with the report that her blood sugar had actually gone high. You see, Bonnie's husband is diabetic and so she has access to a home blood sugar test. On that day she had felt unusually poorly and just out of curiosity had checked her blood sugar and it was running up near 140. Now, this is not an extremely high blood sugar -- certainly not in a diabetic range -- but, it is higher than normal, and certainly higher than you would expect in someone who is a glucogenic hypoglycemic. We were concerned that the Oxygenic G had pushed her blood sugar up. So, we told her to decrease it to just 1 daily as a precautionary measure, and to report to us if there were any continuing problems. When we saw Bonnie 4 weeks later the source of the problem was apparent in her objective tests. Our concern that treating her as glucogenic had been over-done was unfounded. She still showed a glucogenic test pattern. The problem was that we had never completely taken her off the small maintenance dosage of Oxy D and Oxy D+. Now her test pattern showed a very strong anaerobic pattern. We stopped the Oxy D and D+ completely and boosted the Oxy G back up to the dose indicated by the QRG analysis. Now, Bonnie is a very satisfied lady. Her hot flashes are only a fraction of the frequency and severity that they originally were. Her bladder and digestive function have improved, and she is over all feeling quite well. In addition, she lost 20 pounds in her first 8 weeks of NUTRI-SPEC, "without even trying." Lessons to be learned from these case studies? You are only going to "cure" a patient's symptoms by correcting the cause(s) of those symptoms. You are only going to find the causative factors by looking at fundamental metabolic control systems. You can only effectively evaluate control systems with a systematic, objective analysis. Your NUTRI-SPEC analysis is so complete, yet so concise, you can determine precisely each patient's metabolic needs in just a few minutes.