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Volume 10 Number 6

Guy R. Schenker, D.C.
June, 1999

Dear Doctor,

     You have seen that most of your patients with an 
electrolyte insufficiency imbalance are ...

                    STUCK IN LOW GEAR.

When the physical and emotional demands of life require 
that they punch down the accelerator and zoom joyfully 
down the highway of life -- they are stuck in the slow 
lane behind a truck, choking on its exhaust.

     Which of your highly bio-active NUTRI-SPEC 
supplements will give the most immediate and dramatic 
vitality boost to your EI patients?  You learned last 
month that it is very often your Formula EW -- which is 
primarily glycerol plus a little vitamin E.  Why is 
glycerol such a powerful therapeutic tool?

- It not only influences fluid dynamics but influences 
membrane permeability as well.  It quickly permeates all 
three body fluid compartments, carrying electrolyte 
buffers and other solutes, along with biologically 
activated water to meet physiological demand.

- Glycerol also binds with and neutralizes the free fatty 
acids that are the primary cause of the aging process 
which results from free radical peroxidation -- 
particularly the abnormal fatty acids with conjugated 
double bonds which most accelerate the aging process.

     In other words, glycerol effectively reverses the 
essence of the pathological process that defines our 
NUTRI-SPEC Electrolyte Insufficiency imbalance.  It is 
particularly crucial to your EI patients who have a strong 
oxidative stress (dysaerobic) component to their EI 

                          - 2 -

    The combination of pathological processes which typify 
an EI imbalance (involving fluid and electrolyte dynamics 
plus free radical peroxidation), allows us to picture the 
whole electrolyte insufficiency imbalance as resembling a 
sub-clinical state of shock.  This model was first 
proposed by Rivici many years ago.  Both the free radical 
damage and the aberrant fluid dynamics of your EI patients 
are precisely the findings in patients with either heat 
shock or hemmorhagic shock, just milder in degree.

     Based originally on this Rivici model of mild shock 
accompanying low adrenal and kidney function, and the 
resulting stress on the vascular system -- NUTRI-SPEC has 
been using glycerol as a therapeutic agent since 1984.  
Now, many years later, we have quite substantial 
additional evidence in the scientific literature 
supporting glycerol's clinical benefits.

     One study was published in Medicine and Science in 
Sports Medicine in 1990.  It was published under the 
title, "Effects of Glycerol Induced Hyper-Hydration prior 
to Exercise in the Heat On Sweating and Core Temperature." 
This study and others supporting it showed a tremendous 
increase in endurance exercise tolerance when athletes 
loaded with glycerol and water prior to competition.

     I would not be surprised if, based on the latest 
scientific studies, many companies in the nutrition 
supplement industry will jump on the band wagon and begin 
offering glycerol supplements.  Remember that NUTRI-SPEC 
has been using glycerol as a therapeutic agent for more 
than 15 years.  We have pioneered its use and have very 
specific objective protocol indicating when it is 
beneficial and when it will do harm.

     Do harm?  How can a supplement whose clinical power I 
just raved about possibly cause harm?  Remember, you are a 
NUTRI-SPEC practitioner.  That means you understand the 
concept of biological individuality.  Any therapeutic 
agent that has the power to correct one patient's 
metabolic imbalance has the potential to harm a patient 
with the opposite metabolic imbalance.

     Glycerol has a powerful alkalizing effect on the 
systemic level of biological organization, and a powerful 
acidifying effect at the tissue level.  Any patient who 
has an anaerobic imbalance as a primary cause of their 
symptoms will see those symptoms greatly exacerbated by 

                          - 3 -

     Do you begin to appreciate the beauty of your
Quick Reference Guide (QRG) analysis of your patients'
test results?  You have specific objective protocol for
each highly bio-active NUTRI-SPEC supplement, including 
Formula EW.  You know exactly which patients will benefit 
from its therapeutic affect, and which patients will be 
harmed.  Furthermore, you know exactly how much is likely 
to be beneficial and what other nutrients must accompany 
it to maintain balance.

     In the last several months we have completed our 
discussion of electrolyte insufficiency and electrolyte 
stress imbalances as they relate to the sweeping changes 
made last year in your QRG analysis.  Our discussion of 
glycerol leads us easily from our discussion of 
electrolyte and fluid dynamics into a discussion of our 
second fundamental metabolic control system ...


     Your NUTRI-SPEC Anaerobic/Dysaerobic balance system 
is based upon the paradigm developed by Emmanuel Rivici.  
Dr. Rivici was unique in being both a world class 
molecular biologist and a world class clinician.  From 
studying Rivici's work we know that anaerobic/dysaerobic 
problems can be thought of in two ways:

- an imbalance in oxidative metabolism
- an imbalance in lipid metabolism

     Furthermore, Rivici showed that oxidative metabolism 
and lipid metabolism are functionally related in two ways:

- to produce energy with oxygen efficiently
- to control membrane permeability

     Are we talking about anything important here?  When 
we talk about oxidative energy production and the 
selective permeability of biological membranes we are 
talking about ...


     That is why anaerobic/dysaerobic balance is the most 
pervasive of your five NUTRI-SPEC metabolic control 
systems.  Without strength and balance in both anti-
anaerobic and anti-dysaerobic forces, your patient cannot:

- produce oxidative energy in sufficient quantity to power 
the essential activities of a high vitality life.

                          - 4 -

- prevent the oxidative free radical damage that 
accelerates tissue degeneration and aging.

- maintain glycemic control.

- maintain normal fluid and electrolyte dynamics in each 
of the three body fluid compartments.

- maintain normal pH in each of the three body fluid 

     In other words, anaerobic/dysaerobic forces play a 
part in virtually everything that happens in the human 
body.  That is also why virtually any symptom or condition 
you can name is likely to have an anaerobic or a 
dysaerobic component.

     How difficult is it to find and treat an imbalance in 
this vitally important metabolic control system?  Finding 
it takes less than 20 seconds using your QRG.  Treating it 
is as simple as selecting from only a half dozen 
supplements as per your QRG protocol.

     Look at your QRG now.  Look at the anaerobic/
dysaerobic section of page one and just imagine that you 
as a clinician so easily have ...


     Look at the 3-point quick scan.  These three tests, 
the surface tension, the oxidative index and the adjusted 
urine pH allow you in less than 10 seconds to eliminate 
this imbalance from consideration if your patient has no 
obvious problem here.  If you do find a potential problem 
when considering this 3-point Quick Scan you need only 
consider two additional tests -- the adjusted saliva pH 
and the dermographics line to either confirm or rule out 
the need for an anaerobic/dysaerobic treatment regimen for 
this patient.

     Having found an anaerobic/dysaerobic imbalance, you 
need take another minute to work through the anaerobic/
dysaerobic supplement page of your QRG to determine which 
of the five supplements your patient needs and in exactly 
what quantities.

     And what amazing supplements they are.

     Pick up a bottle of Oxygenic A and a bottle of 
Oxygenic D.  Read through the lists of ingredients and ask 
yourself just what it all means.  Oxygenic A gives your
                          - 5 -

anaerobic patient every vitamin, every mineral, every 
trace mineral and every amino acid needed to reverse the 
causes and the effects of insufficient oxidative energy
production.  Similarly, Oxygenic D provides all the
vitamins, all the minerals, all the trace minerals and all 
the amino acids essential to reverse the causes and 
effects of free radical peroxidation.

     Now consider your Oxygenic A-Plus and Oxygenic 

                   YOU WILL EVER FIND.

While the Oxy A and Oxy D provide the nutrient raw 
materials, it is the Oxy A-Plus and the Oxy D-Plus which 
drive the mechanism.  By that I mean two things:

- The membrane permeability is repolarized such that fluid 
and solutes (including all the juicy ingredients of Oxy A 
or Oxy D) are able to flow to their site of activity.

- The spark is provided to fire up the metabolic engine -- 
Think of the Oxy A and D as the fuel being sucked into a 
car's engine, while the Oxy A+ and D+ are the spark that 
ignites the fuel.

     You cannot correct your anaerobic/dysaerobic patients 
with Oxy A and Oxy D alone any more than you can make your 
car run by dousing the engine with a gallon of gasoline.  
The fuel has to be put exactly where it needs to be and 
must be energized.  That is the role of your Oxygenic A+ 
and D+.  These are the therapeutic agents that make the 
typical clinical nutritionist look impotent compared to 
you and NUTRI-SPEC.

     Consider that Rivici tested literally hundreds of 
biologically active substances for their metabolic 
effects.  Out of all those substances he selected the 
ingredients of your Oxygenic A+ and Oxygenic D+ to use for 
their powerful and immediate impact on body chemistry.  He 
used these two supplements exclusively for nearly 40 years 
as his sole means of controlling metabolic balance at the 
tissue and systemic levels.

     Let us look just a bit closer.  Consider Oxygenic D+.  
Recall all that was said above about the effects of 
glycerol in your Formula EW in its control of fluid and 
electrolyte dynamics, tissue pH and the neutralization of 
free radical peroxidation.  Glycerol is just one 
ingredient of Oxygenic D+.  Everything that was said above
                          - 6 -

regarding glycerol applies to Oxygenic D+.  Take the 
anti-dysaerobic power of Formula EW and multiply it 
perhaps by 10 and that is what you have with Oxygenic D+.


     And what about Oxygenic A+?  Here you have a 
combination of magnesium (arguably the most clinically 
important of all the macro minerals) combined with 
negative valence sulfur.  The negative valence sulfur is 
the key to innumerable biochemical processes.  It 
constitutes the active functional group in such diverse 
compounds as glutathione, cysteine, taurine, and 
methionine.  Just think of it as promoting normal 
oxidation, while protecting against the tissue damage that 
accrues from insufficient oxidation.

     It is no exaggeration to say that you could build an 
entire nutrition practice on nothing more than the 
judicious use of Oxygenic A-Plus and Oxygenic D-Plus (plus 
Oxy B to provide trace minerals, of course).

     Glancing at the rest of your QRG page for 
Anaerobic/Dysaerobic supplementation you see three other 
supplements that are frequently a useful adjunct for 
either your anaerobic or dysaerobic patients.  These other 
supplements are already critical ingredients in your 
Oxygenic A or Oxygenic D.  Many patients, however, will 
benefit at least temporarily from extra dosages of these 
supplements.  These are so amazing in their clinical power 
that each one could be the subject of an entire issue of 
this Letter.  Use them according to your QRG protocol and 
you will be astounded at their clinical impact 

(particularly when they accompany Oxy A+ or Oxy D+).

     Clinical excellence is easily attainable (but only 
attainable) when you are guided by objective test 
procedures.  When you can objectively quantify each 
patient's status with respect to fundamental metabolic 
control systems, and then -- as you can with NUTRI-SPEC 
supplements -- restore strength and balance to those 
control systems, you have the basis of a highly successful 
practice -- effectively serving a broad diversity of 
enthusiastic patients.


                             Guy R. Schenker, D.C.


Nutri-Spec Letters