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Volume 8 Number 4

Guy R. Schenker, D.C.
April, 1997

Dear Doctor,

     Let me ask you this ...


     If you have been doing NUTRI-SPEC in earnest for any 
length of time you may already have enjoyed that most 
satisfying clinical experience.

     Am I speaking in exaggerated sensationalistic terms 
here?  Absolutely not.  You know that cardiovascular 
disease kills fifty percent of all Americans.  Think of 
that.  Half the people you know -- half your patients, 
half your friends, and half your family are going to die 
of cardiovascular disease.  Then, think of this -- nearly 
every person who suffers from cardiovascular disease has a 


     Now, consider that your NUTRI-SPEC protocol for 
electrolyte stress (as presented on page one of your Quick 
Reference Guide) has proved effective in many hundreds of 
patients across the country in stopping cardiovascular 
disease in its tracks.  Do you fully appreciate how 
significant it is that hundreds of people have had this 
condition (that was ultimately going to kill them) slowed 
at the very least, almost always stopped, and in many 
cases reversed?

     Yes, with NUTRI-SPEC you will save lives.  It bears 
repeating what I have said many many times --

                          - 2 -

     You will see countless cases of high blood pressure 
brought under control.  Many of those patients will 
actually be able to eliminate their blood pressure 
medications entirely.  You will see patients with 
claudication regain the power to walk.  You will see 
patients with congestive heart failure increase their 
functional capacity tremendously, while adding many many 
years to their life.

     Now, think of just one more thing -- your NUTRI-SPEC 
protocol for treating electrolyte stress imbalances has 
recently become at least twice as effective as it has ever 
been before.

     A couple of months ago you were given your new Quick 
Reference Guide page for electrolyte stress.  On that page 
you found listed several new supplements, including 
Formula ES, Taurine, Histidine, Methionine, and Magnesium 
Chloride.  These supplements joined your old standbys -- 
the dispersing agents, di-potassium phosphate, and 
potassium citrate, along with Oxygenic A-Plus, Complex S, 
and Phos Drops.  Each of these supplements has an amazing 
impact on the underlying causes of cardiovascular disease.  
Let us look at each of the new supplements now with a 
description of when and why you use it for electrolyte 
stress patients.  We will begin with our newest      
product ...

                       FORMULA ES.

     This is a product that I formulated nearly ten years 
ago.  Why did it take so long to become available for you?  
It has simply been a matter of price.  Many of the  
ingredients in Formula ES are extremely expensive.  Until 
recently NUTRI-SPEC simply was not big enough to be able 
to purchase the raw materials in sufficient quantities to 
provide a product for you and your patients that was 
reasonably priced.  Now we have achieved not only a 
reasonable price but an amazing price.  If you and your 
patients had to purchase as separate products each of the 
phenomenal ingredients you obtain in Formula ES it would 
cost you many hundreds of dollars a month -- thousands of 
dollars per year.  Formulating a single product containing 
all these ingredients cuts an estimated eighty percent off 
your cost.

     Now let us list these amazing ingredients:

                          - 3 -

- L-Carnitine
- Coenzyme Q 10
- Magnesium (as Aspartate)
- Bromelain
- Chondroitin-4-Sulfate (Chondroitin Sulfate A)

Anything there look familiar?  Certainly you have heard of 
most of these ingredients, as they have almost all been 
heavily hyped at one time or another by the supplement 
industry.  Now let's look at exactly what you can expect 
from Formula ES and why each of these ingredients has such 
a tremendous impact on cardiovascular disease.

                   CHONDROITIN SULFATE

     Of all the amazing ingredients in Formula ES, 
chondroitin sulfate gives you the greatest power over 
cardiovascular disease.  Before we describe the biological 
activity of this amazing substance let us make one thing 
perfectly clear with respect to your Formula ES -- it does 
not contain some crude cartilage concentrate passed off as 
chondroitin sulfate.  This is the real thing.  This is 
chondroitin-4-sulfate, the biologically active compound 
(also known as chondroitin sulfate A).  There are a lot of 
companies out there selling products they call chondroitin 
sulfate which are nothing more than dehydrated powdered 
beef trachea.  That crude substance has a tiny fraction of 
the biological activity of your Formula ES  -- and quite 
frankly, isn't worth a fraction of its cost.

     Now, here is the spectacular story of chondroitin 
sulfate, a supplement I have wanted to give you for ten 

      Chondroitin sulfate (CS) has many important 
functions in human physiology.  Many of those functions 
relate to the structure and function of joints and other 
connective tissues.  The importance of CS to connective 
tissues will be discussed in future Letters.  For now, let 
us concentrate on the most important function of CS -- the 
protection of the cardiovascular system.

     CS helps maintain arterial elasticity.  (Remember, 
arteries are largely connective tissue.)  CS retards the 
arteriosclerotic and aging processes within the arterial  
wall.  CS also possesses lipid clearing activity.  It 
lowers cholesterol; it lowers triglycerides; and it 
normalizes the ratio between HDL, LDL, and VLDL.  CS 
supplementation has also been shown to significantly 
reduce angina pectoris in CVD patients.  In addition to 
clearing lipids (both intra and inter cellular) and
                          - 4 -

maintaining arterial elasticity, CS has been found to 
protect against thrombus formation.

     Sound good so far?  Do you begin to get the idea that 
Formula ES might be the most important thing you can do to 
stop and prevent cardiovascular disease in you patients?  
Read on, there is more.

     It has been known for more than 25 years that 
chondroitin sulfate has a powerful impact on reversing 
cardiovascular disease.  As early as 1969, two studies 
were cited in JAMA demonstrating the tremendous clinical 
effects of CS.  In both studies, the number of coronary 
incidents (myocardial infarction, coronary insufficiency, 
myocardial ischemia, and congestive heart failure) in CVD 
patients treated with CS was about 1/6 the number reported 
for the control patients who received no CS.

     In addition to the striking reduction in mortality 
and morbidity in patients with ischemic coronary heart 
disease, the Institute for Arteriosclerosis Research at 
Loma Lind University School of Medicine reports 
experimental studies showing that ...


CS is found to clear lipids in tissue, stimulate cellular 
metabolism, increase turn-over of fatty acids at the 
cellular level, and increase RNA and DNA synthesis in 
tissue cultures.

     How does CS work these wonders?  Quite simply (to put 
it in NUTRI-SPEC terms), it reverses an Electrolyte Stress 
Imbalance.  Just what is an Electrolyte Stress Imbalance?  
It is the destruction of the electronegative colloidal 
properties of the body fluids.  Once the polarity of the 
body fluids begins to drop (in association with excess 
electrolyte load and with the loss of tissue membrane 
integrity associated with many of the NUTRI-SPEC 
imbalances) you get a vicious cycle.  The loss of     
electronegativity accelerates the rate of tissue 
destruction -- and the rate of tissue destruction further 
decreases the electronegativity.

     In a broad generalization it could be said that ...


                          - 5 -

     CS is a polyanionic component of cell walls and 
intracellular and intercellular fluids.  The ion exchange 
properties of CS are involved in the transfer of 
electrolytes and nutrients through cell walls.  CS occurs 
in the organic matrix of connective tissue throughout the

     What are some of the things that happen as 
Electrolyte Stress Imbalance progresses?  One major 
problem is the flocculation of the body fluids.  The red 
blood cells begin to clump.  In the presence of adequate 
chondroitin sulfate the rouleaux formation of RBCs is 

     The other thing that happens along the lines of 
flocculation is that platelets begin to aggregate.  
Photomicrographs taken within arteries show that CS works 
by inducing electronegative charges on platelets.  The 
maintenance of the normal electronegative charge prevents 
the platelets from aggregating and adhering to one 
another, thereby lowering the tendency for developing 

     Another interesting activity of CS which directly 
impacts one of the major factors involved with Electrolyte 
Stress Imbalance is that CS increases the excretion of 
sodium.  Remember, sodium is the salt whose excretion by 
the kidneys is most limited in your electrolyte stress 

     The cholesterol and triglyceride lowering capability 
of CS is also tied in with its effect on maintaining the 
normal body colloid.  It is only when damage to the 
arterial intima creates a loss of tissue membrane polarity 
that cholesterol and the other components of 
atherosclerotic plaquing are pulled into the lesion.  CS 
prevents the accumulation of lipids in atherosclerotic 
lesions.  But it does even more than that -- it can 
actually reverse these lesions.  This gets into what we 
call "oral chelation."

     Oral chelation is the process of not just preventing 
arterial plaquing but actually breaking up and eliminating 
those plaques.  Chondroitin sulfate achieves this.  It 
acts in much the same way as the chelating agent EDTA.  It 
goes into the atherosclerotic lesion and breaks it apart 
by grabbing the calcium contained in the plaque.

     [Interesting side note:  The plaques on arterial  
walls contain cholesterol.  It is therefore recommended 
(by the "experts") that we decrease our cholesterol intake
                          - 6 -

to avoid atherosclerosis.  Arterial plaques contain even 
more calcium molecules than they do cholesterol -- yet you 
don't hear anyone suggesting we restrict our calcium 
intake to avoid hardening of the arteries.]

     CS is the only substance that is calcium specific in 
its chelating ability.  In other words, it has the ability 
to go in and grab calcium, rip it out of a plaque, carry 
it to the kidneys and eliminate it -- and not grab any 
other important mineral nutrients at the same time.      

     The biggest problem with EDTA chelation therapy which 
is becoming so popular for cardiovascular disease is that 
the EDTA used as a chelator has no discriminating 
capability whatsoever.  Yes, it grabs calcium and it grabs 
toxic heavy metals, but at the same time it takes all your 
zinc and your copper and your maganese and your selenium 
and all your other important trace mineral nutrients.  The 
long term damage from trace mineral depletion can outweigh 
the short term benefit of the chelation.

     The oral chelation effect of chondroitin sulfate is 
further enhanced by another ingredient in your
Formula ES ...


     Bromelain is a proteolytic enzyme that has the 
capacity to break down arterial deposits.  The use of 
bromelain as an oral chelating agent was pioneered by the 
famous German doctor Hans Nieper.  To get any chelation 
benefits from bromelain as a sole therapeutic agent 
requires tremendous doses of this enzyme.  At a fraction 
of the cost we have given you enough bromelain in Formula 
ES to potentiate the much greater chelating effect of CS.  
In other words, chondroitin sulfate plus a little 
bromelain will give you a much more effective oral 
chelation than the mega doses of bromelain employed by 
those who follow Nieper's regimen.

     Next month you will get the complete scoop on the 
biological activity of the other ingredients in your 
Formula ES.  Meanwhile, waste no time in putting Formula 
ES and the rest of your Electrolyte Stress protocol to 
work for all your patients with CVD.  There is no more 
valuable professional service you can offer.


                        Guy R. Schenker, D.C.
     We have recently completed some dramatic changes in 
your NUTRI-SPEC analytical system of clinical nutrition.  
These changes give you three big advantages:

a.  The tests are easier and faster to perform.

b.  The test interpretation is much easier.

7.  Your analysis is much more specific -- more clearly     
    defining each patient's individual needs.

A.  Changes in the test procedures:

    1.  The following tests have been entirely deleted 
from your testing procedure:

        a.  The second of the three blood pressures.
        b.  The pilomotor reflex.
        c.  The Sargent's Line reflex.
        d.  The pupil reflex.

    2.  The following tests have been added:

        a.  An adjusted saliva pH
        b.  A fourth pulse

B.  Changes in Your Quick Reference Guide:

    1.  We are giving you an entirely revised Quick 
Reference Guide.  It follows the same format of each page 
representing the analysis of one of the five NUTRI-SPEC 
fundamental balance systems.  There are, however, these 
important improvements:

        a.  The top of each page gives you just a few       
    quick tests to determine whether this patient is a      
    likely candidate for the imbalance under                
    consideration.  In other words, if a "Quick-Scan" of    
    your patient's tests does not reveal an obvious         
    tendency toward one imbalance or its opposite,          
    you need look no further -- just turn the page and      
    consider the next imbalance.

        b.  The ranges of abnormal results for each test    
    are much more specifically defined in this new Quick    
    Reference Guide.  This will eliminate any subjective    
    guess work on your part.

        c.  The supplement recommendations available for    
    you to give your patients have been greatly expanded.

        d.  The parameters indicating the need for each     
    supplement are very specifically defined.

                   ADJUSTED SALIVA pH:

     A chart is printed right on your Test Results      
Form showing you how to convert your patient's saliva       
pH to the adjusted saliva pH.  You add or subtract the      
number of tenths to the saliva pH indicated by the          
patient's specific gravity.  Enter the adjusted saliva      
pH next to the saliva pH on the Test Results Form.

There are two major determinants of saliva pH:

- the electrolyte content of the saliva
- the carbon dioxide plus carbonic acid level of the 

     All the patients whose saliva pH is either high or 
low in association with low or high electrolyte levels 
(whether or not the saliva pH and electrolyte levels were 
the result of an electrolyte imbalance or some other 
NUTRI-SPEC imbalance) have a urinary specific gravity that 
varies inversely with the saliva pH.  Every patient who 
has a high saliva pH with low saliva electrolytes has a 
low urine specific gravity.  Every patient who has an acid 
saliva pH with high electrolyte concentration has a high 
urine specific gravity.

     Factor in this urine specific gravity association 
with saliva pH and we have effectively segregated the two 
major influences on saliva pH.  That is to say, the 
adjusted saliva pH reflects almost purely the carbon 
dioxide plus carbonic acid influence on saliva pH.  These 
organic acids are, of course, the key to the saliva pH's 
association with Anaerobic/Dysaerobic Imbalances, 
Glucogenic/Ketogenic Imbalances, and Acid/Alkaline 


        a.  With the patient supine, and having already     
    taken the patient's saliva pH, measure the patient's    
    first pulse for 15 seconds, multiply by 4 and enter     
    on the Test Results Form.

        b.  Take the patient's respiratory rate for 30      
    seconds, multiply by 2 and enter on the Test Results    

        c.  Take the patient's first systolic and           
    diastolic blood pressures, and record.

        d.  With your watch or timer ready, ask the         
    patient to stand.  Begin timing as the patient's feet   
    hit the floor.  At the 5 second mark begin counting     
    your second pulse, counting seconds 5 through 20.  At   
    the 20 second mark immediately begin counting over      
    again to get the third pulse, counting from seconds 20  
    through 35.  You now have two numbers, for example, 16  
    and 18, representing the second and third pulses.       
    Multiply each by 4 and record on the Test Results       

        e.  With the patient continuing to stand, take the  
    second systolic and diastolic blood pressures and the   
    fourth pulse.  Record the blood pressures and           
    multiply by 4 to get your fourth pulse, and record      
    these three numbers on the Test Results Form.

        f.  Have the patient sit, and test the breath hold  

[As before, the remaining tests (dermographics, cough and 
gag reflexes, and pupil size) may be performed either 
before or after the other tests.]


Nutri-Spec Letters